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Education
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Full Name: Eduardo Gade Gusmao
Full name in native language: Eduardo Gade Gusmão
Date of birth: 02.December.1987
Place of birth: Recife, Pernambuco, Brazil
Citizenship: Brazilian
Research Interests
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2017
2016
2015
2014
2012
2011
Gusmao, E.G., Dieterich, C. & Costa, I.G. Prediction of transcription factor binding sites by integrating DNase digestion and histone modification. Lecture Notes in Computer Science, 7409:109-119, 2012.
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Ullius, A., Lüscher-Firzlaf, J., Costa, I.G., Walsemann, G., Forst, A.H., Gusmao, E.G., Kapelle, K., Kleine, H., Kremmer, E., Vervoorts, J. & Lüscher, B. The interaction of MYC with the trithorax protein ASH2L promotes gene transcription by regulating H3K27 modification. Nucleic Acids Research, 42(11):6901-6920, 2014.
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Gusmao, E.G. & de Souto, M.C.P. Issues on sampling negative examples for predicting prokaryotic promoters. Proceedings of the 2014 International Joint Conference on Neural Networks, 494-501, 2014.
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Gusmao, E.G., Dieterich, C., Zenke, M. & Costa, I.G. Detection of active transcription factor binding sites with the combination of DNase hypersensitivity and histone modifications. Bioinformatics (Oxford Press), 30(22):3143-3151, 2014.
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Hänzelmann, S., Beier, F., Gusmao, E.G., Koch, C.M., Hummel, S., Charapitsa, I., Joussen, S., Benes, V., Brümmendorf, T.H., Reid, G., Costa, I.G. & Wagner, W. Replicative senescence is associated with nuclear reorganization and with DNA methylation at specific transcription factor binding sites. Clinical Epigenetics, 7(1):19-33, 2015.
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Lin, Q., Chauvistré, H., Costa, I.G., Gusmao, E.G., Mitzka, S., Hänzelmann, S., Baying, B., Klisch, T., Moriggl, R., Hennuy, B., Smeets, H., Homann, K., Benes, V., Seré, K. & Zenke, M. Epigenetic program and transcription factor circuitry of dendritic cell development. Nucleic Acids Research, 43(20):9680-9693, 2015.
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Schemionek, M., Herrmann, O., Reher, M.M., Chatain, N., Schubert, C., Costa, I.G., Hänzelmann, S., Gusmao, E.G., Kintsler, S., Braunschweig, T., Hamilton, A., Helgason, G.V., Copland, M., Schwab, A., Müller-Tidow, C., Li, S., Holyoake, T.L., Brümmendorf, T.H. & Koschmieder, S. Mtss1 is a critical epigenetically regulated tumor suppressor in CML. Leukemia, 30(4):823-832, 2015.
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Gusmao, E.G., Allhoff, M., Zenke, M. & Costa, I.G. Analysis of computational footprinting methods for DNase sequencing experiments. Nature Methods, 13(4):303-309, 2016.
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Kolovos, P., Georgomanolis, T., Koeferle, A., Larkin, J.D., Brant, L., Nikolicć, M., Gusmao, E.G., Zirkel, A., Knoch, T.A., Costa, I.G., van Ijcken, W.F., Cook, P.R., Grosveld, F.G. & Papantonis, A. Binding of nuclear factor kappa B to non-canonical consensus sites reveals its multimodal role during the early inflammatory response. Genome Research, 26(11):1478-1489, 2016.
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Axelsson, A.S., Mahdi, T., Nenonen, H.A., Singh, T., Hänzelmann S., Wendt, A., Bagge, A., Reinbothe, T.M., Millstein, J., Yang, X., Zhang, B., Gusmao, E.G., Shu, L., Szabat, M., Tang, Y., Wang, J., Salö, S., Eliasson, L., Artner, I., Fex, M., Johnson, J.D., Wollheim, C.B., Derry, J.M.J., Mecham, B., Spégel, P., Mulder, H., Costa, I.G., Zhang, E. & Rosengren, A.H. Sox5 regulates Beta-cell phenotype and is reduced in type 2 diabetes. Nature Communications, 8:15652, 2017.
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B.Sc. in Computer Science in Federal University of Pernambuco - Recife, Pernambuco, Brazil
Title: Study of methods to identify single nucleotide polymorphism interactions
Advisor: Prof. Dr. Katia S. Guimaraes
2006-2011
M.Sc. in Computer Science in Federal University of Pernambuco - Recife, Pernambuco, Brazil
Title: Prediction of transcription factor binding sites by integrating different epigenetic features
Advisor: Prof. Dr. Ivan G. Costa & Prof. Dr. Marcilio C.P. de Souto
2011-2012
Ph.D. in Life Sciences in RWTH Aachen University - Aachen, Germany
Title: Analysis of computational footprinting methods for next-generation sequencing experiments
Advisor: Prof. Dr. Ivan G. Costa & Prof. Dr. Thomas Berlage
2012-2016
Postdoctoral Fellow in Harvard School of Public Health - Boston, Massachusetts, USA
Title: Integration of CRISPR/Cas9 with droplet-based single-cell sequencing
Advisor: Prof. Dr. Xiaole Shirley Liu
2016-2017
Postdoctoral Fellow in University of Cologne - Cologne, Germany
Title: Computational framework to unravel the interplay between chromatin conformation and gene regulation
Advisor: Prof. Dr. Argyris Papantonis
2018-
Computational "omics" data integration
Machine & Statistical learning
Computational modeling & treatment of NGS-based data
3D chromatin structure
NGS-based technologies data analysis
Gene regulatory landscapes and their DNA sequence motifs
2014
2016
Best Publication at the Day of Medical Research of RWTH Aachen University Medical School. Publication: Gusmao, E.G., et al. Nature Methods, 13(4):303-309, 2016. Award: € 2000.
Araújo, F.R.B., Gusmao, E.G. & Guimarães, K.S. A case-control study of non-parametric approaches for detecting SNP-SNP interactions. Proceedings of the 30th International Conference of the Chilean Computer Science Society, 19-27, 2011.
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Publication Elected for Top-10 2015/2016 Reading List at the RECOMB/ISCB Conference on Regulatory and Systems Genomics. Publication: Gusmao, E.G., et al. Nature Methods, 13(4):303-309, 2016.
Top-3 Methods at the ENCODE-DREAM in vivo Transcription Factor Binding Site Prediction Challenge.
Travel Award to RECOMB/ISCB Conference on Regulatory and Systems Genomics. Award: US$ 1500.
Best Oral Presentation at International Conference of the AB3C and Brazilian Symposium on Bioinformatics (X-meeting/BSB). Title: “Search of Cell-Specific Transcription Factor Binding Sites with DNase Hypersensitivity and Histone Modifications".

© 2017 by Eduardo Gade Gusmao